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(2011) used the histone deacetylase inhibitor depispeptide to reverse DNA hypermethylation and alter the histone modification pattern at GSTP1 promoter, including a reduction of H3K9me2/3 and H3K27me2/3 and an increase of H3K18Ac, thereby inducing GSTP1 mRNA re-expression

Merkuriuz Lek, 11:247-251 (2001)

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Rather than maintaining steady release rates, these neurons demonstrate phasic firing in response to unexpected rewards or reward-predicting cues