Mov Disord 32(7):983990 Cuys E, Verdura S, Llorach-Pars L, Fernndez-Arroyo S, Joven J, Martin-Castillo B, Bosch-Barrera J, Brunet J, Nonell-Canals A, Sanchez-Martinez M, Menendez JA (2018) Metformin is a direct SIRT1-activating compound: computational modeling and experimental validation
It is well-known that there is an interaction between the immune system and the microbiome, involving hormone receptors, various immune mediators, stem cells, different subpopulations of leukocytes, plasma cells, and antibodies such as IgG, IgM, and IgA, along with interleukins and inflammatory proteins
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Brun et al., 1990)