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Their integration offers synergistic advantages: proteomics uncovers dynamic changes in enzyme abundance, post-translational modifications and signaling pathways, wheras metabolomics captures real-time metabolic flux, substrate-product relationships, and metabolic bottlenecks ( This study aimed to elucidate the mechanisms underlying oxidative hippocampal injury in mid-late SAE using an integrated multi-omics strategy
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The mechanistic rationale for adjunctive use is strong
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