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(3) Passive avoidance learning was significantly improved

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Figure 6 Modified Dihexa is not a hair cell protectant To test the specificity of Dihexa for the observed protection, we synthesized an additional Dihexa variant that was missing an N-terminal amino group

Additionally, Shishido et al (80) demonstrated that the adhesion of OC cells to the peritoneal mesothelium is facilitated by the interaction between the OCSC markers CD44 and integrin-1, which are recognized by hyaluronic acid receptors on the mesothelial cell membrane (80)

However, significant translational barriers remain: no human pharmacokinetic data, high synthesis cost, unknown long-term safety, and the absence of clinical trials

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