Transparency: All key data (concentration, dose volume, number of doses) is clearly displayed
Kubota, M
Comparison with other neuroprotective peptides Beyond the Semax and Selank comparison, cerebrolysin can be evaluated against other compounds in the neuroprotective space: Dihexa : A synthetic peptide with extremely potent BDNF-potentiating effects
Reconstitution of lyophilised research peptides
The honest caveat: animal studies especially rat studies do not always translate reliably to humans, and the research here has been dominated by a single group
In murine models of doxorubicin (DOX) and ischemia/reperfusion (I/R)-induced cardiomyopathy, administering DOX to mice induced cardiomyopathy with a rapid, systemic accumulation of non-heme iron via heme degradation by Nrf2-mediated upregulation of HO-1, which effect was abolished in Nrf2-deficient mice (Fang et al., 2019)