A typical nasal pump delivers ~100mcg per spray, so a 300mcg dose = 3 sprays
What the evidence supports today is biological plausibility worth a proper trial
It increases the risk for multiple metabolic complications including type 2 diabetes (T2D), metabolic-dysfunction associated steatotic liver disease (MASLD, previously known as non-alcoholic fatty liver disease), cardiovascular disease as well as many mechanical complications such as osteoarthritis and obstructive sleep apnoea (OSA) [3]
Stimulants: Medications like amphetamines or caffeine can counteract clonidines calming effects, potentially causing insomnia
A healthy nasal mucosa absorbs peptides much better than an irritated one
Here are some natural sources to include in our diet: Cruciferous Vegetables : Broccoli, Brussels sprouts, kale, and cauliflower are rich in sulfur-containing compounds that support glutathione production