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Very common (more than 1 in 10 people): nausea (18-20%), diarrhea (12-15%), decreased appetite (10-12%)

Michels M, Jesus GFA, Voytena APL, Rossetto M, Ramlov F, Crneo E, Feuser P, Gelain D, Dal-Pizzol F (2021) Immunomodulatory effect of Bifidobacterium, Lactobacillus , and Streptococcus strains of paraprobiotics in lipopolysaccharide-stimulated inflammatory responses in RAW-264.7 macrophages

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24 h later, cells were lyzed by 100 L luciferase-reporter lysis buffer (Promega E1531)

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Prolonged alcohol misuse can also contribute to mental health disorders like depression and anxiety