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The Phase 2 dose-finding trial (N=338), published in the New England Journal of Medicine in 2023 (DOI: 10.1056/NEJMoa2301972), randomized participants with obesity (BMI 30-50) to retatrutide at doses ranging from 0.5mg to 12mg weekly or placebo over 48 weeks
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To examine for carry-over effect in the primary and secondary outcomes, the models were fitted with the treatment by period interaction terms
On the treatment of Diabetus mellitus by acid extract of Duodenal Mucous Membrane
Discuss individual treatment goalsweight loss magnitude, metabolic improvement, tolerability prioritiesalongside your provider's assessment of your genetic and metabolic profile
Lose weight quickly and that volume can deplete, leaving under-eye hollows, deeper tear troughs, and a more tired or sunken look even when you feel well
