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The total effect indices provide the contribution of variance in a parameter including the variance of all possible higher order interactions, indicating the importance of any input
Around S = 1.4, the GS flux starts to increase more slowly while the GPX flux still increases at roughly the same rate as S increases, so the GSH curve starts to level off and reaches a maximum at S = 1.8
Any input would be greatly appreciated
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In addition, andrographolide has a protective effect on APAP-induced hepatotoxicity both in vivo and in vitro (Yan et al., 2018)
