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Efficacy and safety of co-administered once-weekly cagrilintide 2.4 mg with once-weekly GLP1 2.4 mg in type 2 diabetes: A multicentre, randomised, double-blind, active-controlled, phase 2 trial
Looking ahead to late 2026, a wave of anticipated new therapeutic indications across a diverse range of clinical areas includes: Potential role as preventive medicines As incretin-based therapies continue to demonstrate a wide range of health benefits, interest is growing in their potential role as preventive medicines
Older adults A 2015 review suggests that adults over the age of 60 may be more likely to have a vitamin B12 deficiency
In addition, some aspects of GLP-1 beyond weight loss, such as preclinical evidence on GLP-1 effects in directly modulating the hypothalamuspituitarygonadal axis, or the effects of GLP-1RA on clinical and biochemical expression of hyperandrogenism, still deserve a greater insight, especially in light of a possible therapeutic use in PCOS women independently of obesity
When more free radicals than antioxidants are present, oxidative cell damage occurs
Coskun T, Sloop KW, Loghin C, Alsina-Fernandez J, Urva S, Bokvist KB, Cui X, Briere DA, Cabrera O, Roell WC, Kuchibhotla U, Moyers JS, Benson CT, Gimeno RE, DAlessio DA, Haupt A
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