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But for patients switching for the right reasons (plateau, intolerable side effects, or a move to a more effective drug), the results at maintenance dose typically justify the temporary inconvenience

These, in turn, have nuanced biological functions

For instance, the outer membrane of Gram-negative bacteria acts as a barrier that prevents many drugs from entering the cell

My job is to exhaust every regenerative option first and with the protocol I just described, I rarely reach this conversation

However, the evidence obtained in RCTs, albeit confounded by a low incidence of VTE events, has yielded inconclusive results [35]

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