Your body makes it
When extrapolated to the national population, these figures suggest that as of early 2025, approximately 1.6 million adults in Great Britain had used GLP-1 or GLP-1/GIP medications to support weight loss in the past year (53.7 million adults 2.9%), of whom 910,000 used them exclusively for weight loss (53.7 million 1.7%)
Its important to start slowly, stay hydrated, and monitor for side effects like nausea or low blood sugar
These findings should be interpreted with caution, since this study is subject to potential confounding, as lifestyle modifications during the 6-month period, such as changes in diet, physical activity, or medication adherence, may have influenced stem cell characteristics independently of semaglutide treatment [58]
Orforglipron also reduced non-HDL cholesterol, triglycerides and systolic blood pressure and decreased high-sensitivity C-reactive protein by 47.7%
All chronic antihyperglycemic and hypotensive medication as well as diuretics had not been changed for at least one month before the study and allowed to be continued in the same dose during the study