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Common side effects include, but may not be limited to: pain or redness at the injection site mild diarrhea pruritus (itching) increased swelling joint pain dizziness headache nervousness or anxiety Serious side effects may include: allergic reactions peripheral vascular thrombosis hypokalemia (low potassium levels) pulmonary edema (fluid build-up around or in the lungs) thrombocytosis congestive heart failure There have been reports of anaphylactic shock and death after the parenteral administration of vitamin B12

This is also consistent with our recent work showing that different ITCs lead to various degree of growth inhibition depending on their side chain structure 74

doi: 10.1074/mcp.M113.032136 27 ShahraraSProudfootAEParkCCVolinMVHainesGKWoodsJMet al

Thus, it is recommended to use fermented pollen which is more acceptable for nutrient absorption by the digestive tract of humans (194, 195) because microbes degrade the external pollen walls during fermentation, and its internal nutrients can easily be consumed (8)

doi: 10.1111/dom.15896 78 HuangYNLiaoWLHuangJYLinYJYangSFHuangCCet al

Plant-derived bioactive compounds and essential oils show broad therapeutic potential for treating infections, inflammation, and chronic diseases