3.2.1.2 Propionate Propionate optimizes metabolic flux to enhance myocardial function while potentially inducing pathological damage through metabolic abnormalities, thus achieving bidirectional regulation of myocardial injury in HF
In the central nervous system (CNS), during embryogenesis and adulthood, efferocytosis by ramified microglia balances cell death and neurogenesis, ultimately supporting brain development, optimizing neuronal connectivity, and ensuring that inflammatory responses remain appropriate and effective [25, 26]
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Neuropsychopharmacology 44:235236