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The landscape of heart failure (HF) management is evolving alongside a deeper understanding of how metabolic dysfunction drives cardiac pathology and the progression of HF, particularly in phenotypes like HF with preserved ejection fraction (HFpEF) associated with obesity

These drugs reduce cardiovascular mortality in patients with obesity

Yes, the prescription drug Ozempic is a GLP-1 receptor agonist used primarily to treat diabetes

Antelmi et al., An impaired autonomic regulation in the post-prandial phase has also been suggested

The European Medicines Agency also expresses serious concerns about adverse event reports linking Ozempic and other GLP-1 drugs to gallbladder complications

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