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Many literatures proved that GLP-1 derivatives performed neuroprotective effects and inhibited neuronal apoptosis ( Figure 1 There are also a type of non-peptide small molecules, which are mainly extracted from herbal medicine, such as Cornus officinalis , Gardenia jasminoides , Rehmannia glutinosa , Lamiophlomis rotata , and Strychnos nuzi ( Even for patients without complications of diabetes, their cognitive functions were still significantly improved ( 3 The neuroprotection of GLP-1RA in experimental stroke Many literatures indicated that GLP-1RA were also considered as the latent intervention strategy against ischemic stroke to improve the pathological symptoms and prognosis

Whether youre a researcher or a science enthusiast, understanding glutamines role can provide valuable insights into cellular metabolism and experimental optimization

Together, GLP-1R, GIPR, and GCGR agonists are expected to see more clinical trial evidence to prove their efficacy and safety in treating obese patients

Wang Z, Gurlo T, Matveyenko AV, Elashoff D, Wang P, Rosenberger M, et al

Clinical trial data from the SUSTAIN and STEP programs indicate that gastrointestinal adverse effects are common with semaglutide

S., Amaro, A., et al