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The real question is not whether something has side effects
In a phase 3, double-blind, randomized, controlled trial, 2,539 adults with a body-mass index (BMI) of 30 or greater, or 27 or greater with at least one weight-related complication, were given weekly subcutaneous injections of tirzepatide (5 mg, 10 mg, or 15 mg) or a placebo for 72 weeks
Med Sci Sports Exerc 40(1):8895 Sartori R, Romanello V, Sandri M (2021) Mechanisms of muscle atrophy and hypertrophy: implications in health and disease
Kahn, S
And it is going to impact the pituitary's release of growth hormone
According to the FDA label, semaglutide is contraindicated in patients with a personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, or prior serious hypersensitivity to semaglutide
