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Kidney and cardiovascular outcomes SURPASS-4 kidney composite HR 0.58, slower eGFR decline (-1.4 vs -3.6 mL/min/1.73m2/yr), UACR -6.8% vs +36.9%

GHK-Cu down-regulates TGF-1 and inhibits Smad2/3 activation

For perimetry, we performed automated visual field testing (Humphrey Field Analyzer, Carl Zeiss Meditec, Jena, Germany) using 302 Swedish Interactive Threshold Algorithm (SITA) standard protocols, quantifying the mean deviation in decibels (dB) of all test locations compared to age-matched controls and defining abnormal perimetry as a mean deviation lower than -2 dB

Some patients notice sleep changes earlier, while body composition changes tend to develop more gradually

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ReadyRx glutathione should be stored according to specific instructions provided with shipments, typically including refrigeration at 36-46F (2-8C) to maintain potency and stability, protection from light by keeping vials in original packaging until use, avoiding freezing which can damage the formulation, and checking expiration dates and discarding expired products appropriately