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Front Genet 10:118 Al Khleifat A, Iacoangeli A, van Vugt JJFA et al

Consistently, the livers of HFD-fed mice showed increased IKK--SSG levels, decreased IKK- phosphorylation, and suppressed NF-B activation when compared to these from control animals

[PMID: 3074361] PubMed record related to this compound for laboratory literature review

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While this warning is primarily based on rodent studies and has not been confirmed in humans, cagrilintide is contraindicated in individuals with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2)