There is mounting evidence that elevated plasma homocysteine (and therefore decreased serum methionine) contributes to congenital neural tube defects
References Bahadoran Z, Mirmiran P, Hosseinpanah F, Hedayati M, Hosseinpour-Niazi S, Azizi F
Physical property changes Lyophilized powder appearance changes indicate moisture absorption or other degradation
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As with all applications, this requires careful medical oversight due to the compounds potency and the limited long-term human safety data available
As it is available as a subcutaneous injection, injection-site reactions (such as redness, rash, or itchiness) can occur 2