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In the context of concurrent GLP-1 agonism which is hypothesised to counterbalance glucagon's hyperglycaemic effects net glucagon receptor stimulation may enhance fat metabolism without causing clinically significant hyperglycaemia

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PMCID: PMC10146734

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The states second-largest insurer, Point32Health (which includes Harvard Pilgrim Health Care and Tufts Health Plan) has said it has no plans to change its coverage of GLP-1s, although it, like Blue Cross, has racked up hundreds of millions of dollars in losses, much of it driven by soaring demand for obesity drugs

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However, BMI is not without its problems

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Nonetheless, further studies are necessary

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