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While berberine shows some hepatoprotective effects in certain contexts, it also undergoes extensive liver metabolism
Glucagon-like peptide-1 receptor agonists in type 2 diabetes: a meta-analysis of randomized clinical trials
Certain patientsparticularly those with a history of migraines, autoimmune conditions, or active infectionsmay be more susceptible to these reactions
A) all generic cos were very low on their GLP1 forecast before the launch - a few 10s of crores at best in the 1st year eg A top co in India had a 10cr first yr sales forecast and is set to do a multiplier of that On top of that fewer than expected cos have launched B) online sales which is the biggest area of growth on GLP1s (pharmacies / Telehealth) doesnt get captured and so is direct sales
Khaykina, E
Histamine in the non-digestive tissues is cleared by the enzyme HNMT, but histamine in the digestive system from bacteria, food, drinks, or an immune response to food allergens is broken down by the DAO (diamine oxidase) enzyme 12
