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Dominant evidence type Early pharmacology, animal-model work, small human PK/PD studies, and limited clinical-development research
A robust immune system is essential for skin health because it protects against infections, inflammation, and environmental stresses that can alter skin appearance
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Dapagliflozin treatment ameliorates HG-induced oxidative stress and apoptosis, as manifested by decreased ROS levels, fewer apoptotic nuclei, and downregulated Nox4 and TGF- expression (124)
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