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Frequently Asked Questions Semaglutide is an FDA-approved injectable medication that mimics the GLP-1 hormone, which: Reduces appetite by slowing stomach emptying Regulates blood sugar to curb cravings Promotes satiety (feeling full longer) Clinical trials show an average loss of 15-20% of body weight when combined with diet/exercise

5,6 Additionally, high glucose levels negatively impact osteoblast function, contributing to bone defects partly through the production of advanced glycation end-products (AGEs), which upregulates sclerostin, an inhibitor of osteoblast activity

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The most recognised adverse effects are gastrointestinal disturbances, such as nausea, vomiting, constipation, gastritis, and diarrhoea

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