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Pascual M, Castilla-Cortazar I, Urdaneta E, Quiroga J, Garcia M, Picardi A, Prieto J

When consuming a high-fat and low-carbohydrate diet, patients with MCD enzyme deficiency may experience worsened clinical symptoms, such as hypoglycemia, metabolic acidosis, and increased urinary excretion of organic acids, etc

They also noted that patients who experienced moderate to severe gastrointestinal adverse events, like gastroparesis, were also more likely to discontinue GLP-1 use

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