The pricing tie-breaker is usually pharmacy choice and provincial coverage rather than the molecule
doi: 10.1093/jxb/eru428 11 DeS.Chavez-CalvilloG.WahlstenM.MkinenK
Schrder H, Marrugat J, Vila J, Covas MI, Elosua R
[1] [4] If more than 4 days have passed, patients should skip the missed dose and resume their regular weekly schedule
Intramuscular injections are reserved for cases where oral treatment is insufficient, poorly tolerated, or where deficiency has caused neurological complications
It becomes more likely as diabetes lasts longer, glucose control remains poor, and other risk factorssuch as hypertension and kidney diseaseaccumulate