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J Mycol Med

Curcumin can reverse insulin resistance or protect RINm5F pancreatic cells from apoptosis induced by nortriptyline by inhibiting the phosphoinositide 3-kinase/AKT/FOXO1 pathway and AKAP150/PKA/PP2B interaction, acting on diabetes caused by antidepressants

In contrast, GSH depletion drives M1 polarization, resulting in heightened secretion of pro-inflammatory cytokines, including TNF-, IL-6, and IL-1 (Kwon et al., 2019)

Your skin may sag more due to Collagen loss

10.1016/j.jtcvs.2005.06.015 J