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As a result, plant-based compounds such as curcumin have garnered increasing attention for their therapeutic potential ( in vitro study, curcumin (1050 mol/L) significantly inhibited the proliferation of endometriotic stromal and epithelial cells, partly by lowering estradiol levels, a key driver of lesion progression ( Curcumin also modulates OS in endometriosis by reducing ROS, lipid peroxidation, and enhancing antioxidant defense via activation of the Nrf2-Keap1 pathway (115)

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