What excites Traci most about this work is what she cant measure
When NNMT is inhibited, nicotinamide remains available for salvage into NAD+ via the NAMPT (nicotinamide phosphoribosyltransferase) pathway
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Animal models extend further, with 90-day rat toxicology data published in 2021 showing no organ damage at doses up to 50mg/kg daily, but extrapolating rodent data to human long-term safety requires caution we don't take lightly
Vitamin D: deficiency blunts the response to peptide therapy and mimics fatigue that patients might otherwise attribute to the protocol
Yucel H, Yucel A, Arbag H, Cure E, Eryilmaz MA, Ozer AB