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Because it modulates a methylation and NAD+ pathway, interactions with other metabolically active compounds cannot be ruled out and have not been characterised in humans
Carrol says
Vitamin B12 is an essential nutrient that plays a critical role in keeping the body functioning correctly
Importantly, folate deficiency should not be treated in isolation if B12 deficiency is suspected, as this can precipitate neurological complications
[1] Because intrinsic-factor-dependent uptake in the distal ileum can be absent in conditions such as autoimmune gastritis, pancreatic insufficiency, or bariatric surgery, the intramuscular or subcutaneous route bypasses gastrointestinal barriers and reliably restores serum concentrations
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