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Based on mutational studies of human GSTs the five H-site residues in positions 10, 12, 111, 208, and 216 were judged to be of particular importance for the ketosteroid isomerase activity (Johansson and Mannervik, 2002

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It affects a natural process in the body that controls blood flow, helping more blood reach injured areas

Unlike other GH therapies, its oral, making it user-friendly

However, it never received FDA approval because the results, while positive, weren't dramatic enough to meet regulatory thresholds for an obesity drug

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