Advantage: Convenient, familiar, non-invasive Challenge: Peptides face proteolytic degradation in the stomach and small intestine Bioavailability: Estimated at approximately 38% based on comparative pharmacology (see below) Transdermal (Patch) Some researchers have explored transdermal patches to deliver peptides: Advantage: Avoids first-pass metabolism and GI degradation Challenge: Intact skin is a strong barrier to peptide penetration Feasibility: Not commonly available commercially
Direktur Artis Fajarko, SE
Dulbeccos modified Eagles medium (DMEM), fetal bovine serum, random primers and SYBR safe DNA gel stain were supplied by Invitrogen, Life Technologies (USA)
Neurotherapeutics 20 (1), 195206
6 mg * Daily Value not established
The practical solution is separation: use vitamin C in the morning and GHK-Cu in the evening, or leave a meaningful gap between them