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They are highly prevalent, affecting up to 80% of women by age 50, especially those in their reproductive years
They concluded current evidence of the skin-whitening effect of glutathione is still inconclusive however there is a trend that glutathione might brighten skin colour at sun-exposed area. A review specifically focusing on topical glutathione (and melanogenesis) found that though topical forms (e.g., GSH 0.5% vs 0.1%) had more effect, the studies were small, short term and lack longterm data
Identity additionally confirmed through molecular ion mass spectrometry (MS Deconvolution)
Although various reports have been published on the issues of PPI in health technology assessment (HTA), most have focused on technical issues, and there has been little discussion on how to adopt them
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