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REDEFINE 1's 68-week endpoint for cagrilintide alone was 11.5% (treatment-policy) / 11.8% (trial-product), with the curve visibly flattening around week 52

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These microbiota-derived metabolites can modulate both the innate and adaptive immune system, as well as directly target tumour cells, thereby regulating anti-tumour immunity and response to immunotherapy

The former can be billed to Medicare Part B

One peptide that has received considerable attention is Epitalon