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Weight loss typically starts in week 12, averaging 13 pounds per week at the 0.25 mg dose, then accelerating to 35+ pounds weekly as you reach therapeutic doses (1.02.4 mg)

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Emergency Contraception (Plan B) Since tirzepatide can affect absorption of oral medications, it may also reduce the effectiveness of emergency contraceptives like levonorgestrel (Plan B), increasing the risk of breakthrough bleeding and unintended pregnancy