The clinical trial data from both Phase 2 (Jastreboff et al., NEJM 2023) and Phase 3 (TRIUMPH-4, Eli Lilly press release December 2025) provide a detailed picture of the weight loss trajectory over time
Whole-grain cereals, legumes (e.g., beans and lentils), nuts, lean pork, and yeast are rich sources of thiamin (1)
Scientific Reports
Guyenet SJ, Schwartz MW
A 2016 study published in Nature Scientific Reports showed GHK-Cu produced no cytotoxicity to human keratinocytes at concentrations up to 5,800 micromolar over 72 hours and did not induce inflammatory biomarkers unlike other copper compounds
autoimmune or inflammatory disorders that may cause muscle wasting, such as myasthenia gravis, rheumatoid arthritis, lupus, polymyositis or dermatomyositis