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The exact timing depends on the injury type, baseline tissue condition, and individual response rate

Additionally, epicatechin ( 19 ), a starter unit for proanthocyanidins 33 , is produced cytosolically from cyanidin ( 8-AH + ) by the enzyme anthocyanidin reductase (ANR) (Extended Data Fig

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However, as the locations of the two polar residues are distinct, the receptor interaction sites are also different

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