Gastrointestinal adverse events of metformin treatment in patients with type 2 diabetes mellitus: a systematic review and meta-analysis with meta-regression of observational studies
Ozempic and other GLP-1 receptor agonists are FDA-approved to treat type 2 diabetes
If anything, a trend towards increased weight gain was noted with a longer duration of therapy
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The drugs initially were developed to treat diabetes, before their weight loss benefits were observed