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PMC 9890439

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Independent predictors of amputation identified in the study included prior amputations, male sex, non-Asian ethnicity, history of PAD, history of neuropathy, albuminuria, and elevated HbA1c levels at baseline.38 While this finding was not replicated in other randomized clinical trials on SGLT-2 inhibitors, it is recommended to conduct a thorough screening for risk factors for amputations when initiating SGLT2 inhibitors

T.et al (2024)

It can cause side effects such as nausea, vomiting, stomach upset, heartburn, diarrhea, and seizures

doi: 10.1016/j.nfs.2015.07.001 158