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All authors have read and approved the manuscript
Antioxid Redox Signal 2017;27:9891010
The accomplishment of wound healing includes resolution of all four major events (vessel constriction, the primary platelet plug, the secondary plug, and resolution of the clot) (Stupnisek et al., 2012
It also slightly elevates the possibility of cancer with prolonged high doses
By modulating epigenetic remodeling and metabolic reprogramming within trained immunity pathways, it is possible to develop targeted therapies that reprogram inflammatory memory in myeloid cells at its source
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