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These findings underscore the potential of epigenetic aging measures as biomarkers of liver disease severity and therapeutic responsiveness

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INTRODUCTION G protein-coupled receptors (GPCRs) mediate diverse physiological processes through selective modulation of cellular function and thus represent important drug targets (Hauser et al

288 Regulating cAMP cAMP plays a protective role in COPD inflammation through its effector proteins EPAC and PKA

It comes in two FDA-approved forms, both weekly injections: Mounjaro: type 2 diabetes (2.5 to 15 mg) Zepbound: obesity (2.5 to 15 mg) and moderate-to-severe obstructive sleep apnea in adults with obesity (approved December 2024) No oral tirzepatide exists as of April 2026

Can J Biochem