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The primary limitation relates to the modest sample size and short intervention duration, which may limit precision and long-term inference but does not substantially undermine internal validity under JBI criteria

Conclusion: Understanding semaglutides half-life so you can plan accordingly Semaglutide stays in your system longer than most medications

Patients should always consult the patient information leaflet for their specific GLP-1 formulation and contact their GP or pharmacist if storage guidelines have been breached

Rather than pushing intake higher, protein helps meals feel more complete and steady

GLP-1RA intervention was not associated with higher diarrhea events when compared to the patients given metformin or placebo (OR = 2.06