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However, consumption of any type of vegetarian diet dramatically increases the prevalence of vitamin B 12 deficiency in individuals across all age groups (127, 128)
The necessary reaction requires vitamin B12 in the form of methylcobalamin as a cofactor
Mitochondria-Fundamental to Life and Health
Vitamin B12, or methylcobalamin, is essential to growth, cell reproduction, hematopoiesis, and nucleoprotein and myelin synthesis
National Institute of Standards and Technology
AMPK receptors can desensitize with chronic activation, reducing MOTS-c efficacy over time
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