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Thus, the role of DHARs in ascorbate recycling remains controversial

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Furthermore, in light of more recent data on the possible effect of Se on insulin resistance and the risk for type 2 diabetes, the upper tolerable limit has been further reduced to 255 g/day by the latest EFSA recommendations from 2023 (51)

doi: 10.1073/pnas.79.2.345 2 LundPKGoodmanRHHabenerJF

A patient may need a strength that isnt commercially availablea higher or lower concentration of a retinoid, a non-standard percentage of hydroquinone, or a steroid potency between two available commercial products