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Therefore, our data suggest that GS suppresses IL-1-induced PGE 2 production by inhibiting COX-2 N-glycosylation and this factors subsequent inactivation

Consistently, an increase of cisplatin-induced cytotoxicity following combined treatment with BSO and cisplatin was observed, which may be attributed to a reduction in GSH availability to form platinum conjugates and thereby the reduction of cellular efflux of the drug

Ipamorelin selectively binds to the growth hormone secretagogue receptor type 1a (GHSR-1a), triggering Gq/11-dependent signaling pathways

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10.1021/bi300454k 99 SarkarM