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Long-term evidence indicates that GLP-1 therapies can provide sustained weight reduction, improvements in glycemic control, and favorable cardiometabolic changes when combined with lifestyle modifications and appropriate clinical follow-up

Clinical trials of semaglutide demonstrate average weight loss of 35 pounds by week 4, with momentum accelerating through months two and three as patients adapt to smaller portions and reduced snacking

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According to Patrick Welch, PharmD, BCACP, incorporating lifestyle adjustments significantly improves results

Headache and visual parameters were also comparable between groups (Table 1)