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4 Adverse events in PIONEER 3 1,4 Comparator AE rates are not an adequate basis for comparison of safety between products 1 Because clinical trials are conducted under widely varying conditions, AE rates observed in the clinical trials of a drug cannot be directly compared with rates in the clinical trials of another drug and may not reflect the rates observed in practice 1 AE=adverse event
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10.1073/pnas.91.26.12818 316 KucukkoseC.TaskinA
Avoiding known reflux triggersincluding chocolate, peppermint, citrus fruits, tomato-based products, fatty or fried foods, caffeine, and alcoholmay significantly improve symptoms
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