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Progressive Retinaatrophie (PRA-GUCY2D) Diversität Hereditary ataxia shows symptoms of

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Description

Hereditary ataxia shows symptoms of slow degeneration of the cerebellar cortex

The diseases were reported in mastiff-related breeds (CMR1)

mittleres Risiko

It is generally considered to be congenital in dogs and has been associated with developing glaucoma in later years

Meanwhile the mutations in the gene ATP7B result in defective ATP7B transporter so the copper cannot be properly exported from the liver

Progressive Retinaatrophie (PRA-GUCY2D) Diversität Hereditary ataxia shows symptoms ofRetinal diseases in dogs can be classified as progressive, stationary or developmental. Progressive retinal atrophy (PRA) is a group of degenerative diseases, that affect eyes and lead to blindness in dogs. PRA is a non painful condition in which photoreceptor cells deteriorate over time. The disease starts with a decreased ability to see well at night. There are two main forms of disease: an early onset form, which was first detected in puppies 2 3

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