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Mutation: CNTNAP1 gene
die Hunde wurden zunehmend dünner und starben im Alter von 15 Monaten an Nierenversagen
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Consequently
The inheritable disease is not progressive and the state after eye development remains stable
Primäre Ziliäre Dyskinesie (PCD) - Alaskan Malamute DNA-Profil Mutation: CNTNAP1 genePrimary ciliary dyskinesia (PCD) is a genetic condition affecting motile cilia. Motile cilia are present in the respiratory tract, reproductive tract, brain and spinal cord. They are required for clearing mucous, infectious agents and inhaled dust from the airways. Clinical signs include fertility problems, chronic bronchitis, situs inversus (in about 50% of dogs), bronchopneumonia, bronchiectasis, hydrocephalus, chronic recurrent infections of the
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