Multifokale Retinopathie 1 (CMR1) Für Tierbesitzer Dogs with severe form of

Dogs with severe form of the disease may not live past the first few days of diagnosis while dogs with milder form of the disease can survive several years

0 is possible at any time without complications

resulting in their distinctive elliptical shape

Identifikation von Trägern und betroffenen Tieren für eine gezielte Zuchtplanung

skin and nails

Multifokale Retinopathie 1 (CMR1) Für Tierbesitzer Dogs with severe form ofCanine multifocal retinopathy (CMR1) is an autosomal recessive genetic eye disorder similar to Best macular dystrophy in humans. Causative mutation in BEST1 gene generates a premature stop codon, which results in non functional protein responsible for proper formation of pigment epithelium in retina. Typical clinical findings include multifocal areas of retinal elevation which progress to multifocal areas of outer retinal atrophy. In affected animals,